Diabetes, Obesity, and Stroke


According to Xiquan Zhang, Patent foramen ovale (PFO) has been implicated in the pathogenesis of cryptogenic stroke, arterial desaturation, decompression illness, and migraine. Percutaneous PFO closure is an option for patients with a cryptogenic stroke caused by the paradoxical embolism through the PFO. Among patients with PFO and cryptogenic stroke, closure has reduced recurrent stroke and has a statistically significant effect on the composite of stroke, transient ischemic attack (TIA), and death in adjusted analyses. Percutaneous closure is the preferred treatment, because it results in a smaller wound and a lower rate of postprocedural complications than open heart surgery.



 


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